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449 Modern pharmacological studies have further demonstrated that rhubarb can inhibit the MAPK signaling pathway, thereby alleviating AP-related pathological damage
It runs for 80 weeks (the longest in the program), enrolls a general obesity population without type 2 diabetes, and is designed to be the direct apples-to-apples analogue of SURMOUNT-1 (tirzepatide) and STEP-1 (semaglutide)
Glucagon-like peptide 1 (GLP-1)
For that population, a separate trial called SLIM LIVER provides the most directly relevant evidence so far
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