While some people can obtain adequate B12 from a balanced diet, others may need injections, especially if they have absorption issues or dietary restrictions
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To find suitable ratios, discover interaction effects, and confirm combination regimen safety across populations and metabolic circumstances, robust dose-optimization studies are needed
While animal studies show a good safety profile, a theoretical risk involving its pro-angiogenic effects and potential cancer promotion is a point of consideration, though no evidence has supported this risk in practice