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Humbert, P

Participants were randomly assigned to receive either 120 mg of orlistat or a placebo three times daily, in conjunction with a hypocaloric diet during the first year, followed by a weight maintenance diet in the second year

pmid:11983178 25

Treatment regimen estimand This estimand is used to assess the average treatment effect of bimagrumab, semaglutide or bimagrumab plus semaglutide for all randomized participants at week 48, regardless of treatment adherence and/or premature discontinuation of study treatment or placebo

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