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NICE guidance recommends initial treatment with hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance therapy

When adverse effects do occur following high-dose B12 administration, they are typically mild, transient, and often related to the route of administration rather than the vitamin itself

Correcting a deficiency can remove one biological contributor to low mood, and some people notice less irritability and a more positive outlook

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Omitting Modifier -25 on same-date E/M: The clinician performs an E/M for a separate problem alongside the wound repair but submits both codes without Modifier -25 on the E/M