In April 2025, a federal judge dismissed a proposed class action lawsuit against Bristol Myers Squibb, which alleged the company illegally maintained a monopoly over Pomalyst
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The result showed that the protein expressions of PI3K, P-Akt and m-TOR were highest in group 3, lowest in groups 1 and 2, and significantly increased in group 4 than in group 5, but they did not differ between groups 1 and 2 (Fig
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Our findings align with previous observational studies on GLP-1 RAs, which generally report no significant association between these medications and increased suicide risk ( The psychiatric safety observed in our study is consistent with findings from major RCTs involving tirzepatide, such as the SURMOUNT trials ( The reduction in suicidal ideation and attempts observed in patients treated with tirzepatide could be explained by several biological mechanisms
