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In addition to these previously fatigue-related reported effects, an increase of lean body mass and appetite were also reported, which may explain the improvement of symptoms with respect to fatigue and quality of life [58]

One study showed that men taking vitamin C supplements twice a day for 2 months increased sperm motility by 92%

Ethics declarations Ethics approval and consent to participate The project was ethically approved by the Ethics Committee of Kaohsiung Chang Gung Memorial Hospital

Utilizing characteristics of the tumor microenvironment, such as acidic environments or excess glutathione, can significantly enhance drug accumulation in tumor cells while reducing toxicity to normal cells (153)

This phenomenon was also observed in a study in which the total fat source was substituted with ASTX and flaxseed oil in animals fed a HFD (52)