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To test if GLP-1R agonism can increase blood ethanol levels, a fixed dose of ethanol (2.5 g/kg) was administered by a single gavage or intraperitoneally to C57BL/6N mice, and serum ethanol concentration was measured at 30, 90, 150, 270, and 330 min
PMC2757071 Bodart V, Febbraio M, Demers A, et al
5-N,6-N-bis(2- fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine (BAM15), AICAR, mitochondrial open reading frame of the 12S rRNA-c (MOTS-c)
Liraglutide (Saxenda) NICE Technology Appraisal TA664 recommends liraglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, within a specialist weight management service
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