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Abstract Alzheimers disease (AD) is a multifactorial neurodegenerative disorder described as progressive cognitive decline and neuronal dysfunction, affecting millions globally

At the end of the original 72-week study, people on the highest dose of either medication were randomized into two arms: the treatment group taking a once-daily dose of orforglipron and a placebo control group

Third, the two medications reach peak blood levels at different rates, which influences the timing and intensity of symptoms