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Mice were housed in a specific-pathogen-free facility with a 12 h light (7am-7pm)/12 h dark (7pm-7am) cycle, and cages were changed weekly to refresh diet and ALPHA-dri TM bedding (Shephard Specialty Papers, Watertown, TN)

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Side effects and safety 6 Wegovy side effects you need to be aware of Wegovy and Wegovy HD (semaglutide) are GLP-1 weight-loss medicines that can be associated with common stomach side effects like nausea, vomiting and diarrhea

Users consistently report better outcomes with the combination than with either peptide alone, particularly for stubborn chronic injuries and post-surgical recovery

One 2025 review in Osteoporosis International found that GLP-1s enhanced bone remodeling and also decreased bone mineral density over time, leaving the authors to raise questions over the possibility of future bone fractures