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Mutations in the superoxide dismutase enzyme (which stabilizes superoxide radicals and is implicated in the pathology of certain kinds of ALS) can decrease its affinity for zinc and cause it to become toxic to motor neurons
Notch activation enhances mesenchymal stem cell sheet osteogenic potential by inhibition of cellular senescence
Findings: Preclinical data showed increased collagen-related gene expression and improved tissue remodeling processes
Cuproptosis may collaborate with CD8 + T cells by inducing innate DAMPs that enhance T cell recruitment
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