Withdrawal from GABAergic acting sedative-hypnotic drugs causes acute GABA-under-activity as well as glutamate over-activity which can lead to sensitization and hyper-excitability of the central nervous system, excito-neurotoxicity and increasingly profound neuroadaptions. Wikipedia Kindling (sedative-hypnotic withdrawal) Similarities Between Kindling in ME/CFS and Other Kindling Disorders ME/CFS shares many symptoms with benzodiazepine withdrawal syndrome including: agitation, chest pain, dizziness, fatigue and weakness, flu-like symptoms, irritable bowel syndrome, hot and cold flushes, orthostatic intolerance, restless leg syndrome, stiffness, tachycardia, sensitivity to touch and sound, indecision, etc
Lancet 388 , 787796 (2016)
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[Normal storage condition= Dry, well-ventilated place at 15-25C with no major temperature fluctuations] Precaution For external use only
In addition, steroids have well-documented side effects, including increasing the risk of infection, which already is substantial in patients with alcoholic hepatitis
