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Additionally, the nuclear export signal (NES) in KEAP1 has been shown to be important for NRF2 regulation, as it was found to facilitate the transport of the NRF2-KEAP1 complex out of the nucleus, which terminates NRF2-mediated antioxidant signaling after stress [16]

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Studies in ruminant species such as sheep and cattle reveal that small antral follicles can still be found during pregnancy, but they generally become atretic instead of achieving preovulatory maturity

In regions where soil is low in selenium, deficiencies can impair GPx1 expression significantly, as this isoform is particularly sensitive to intake levels