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They were sued in August 2023 by a Louisiana woman Jaclyn Bjorklund, who alleged the companies downplayed the severity of the gastrointestinal events caused by Ozempic and Mounjaro, and in particular played down the risk of gastroparesis, which is the slowing or stopping of the digestive system

5,6 Additionally, high glucose levels negatively impact osteoblast function, contributing to bone defects partly through the production of advanced glycation end-products (AGEs), which upregulates sclerostin, an inhibitor of osteoblast activity

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Nat Rev Endocrinol (2020) 16:6156