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Riboflavin is also a co-factor for pyridoxine phosphate oxidase, the enzyme required for vitamin B6 production (as pyridoxal 5-phosphate) which is, in turn, an essential cofactor for the enzymes cystathionine-b-synthase (required for the conversion of homocysteine to cysteine) and cystathionine g-lyase (required for the conversion of cysteine to glutathione)

Minerals, on the other hand, are not antioxidants themselves

Rubicon depletion in adipocytes was also shown to reduce body weight and sWAT, vWAT, and BAT mass [83], indicating that inhibiting autophagy may postpone metabolic diseases during aging

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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Marchesini G., Brizi M., Bianchi G., Tomassetti S., Bugianesi E., Lenzi M., McCullough A.J., Natale S., Forlani G., Melchionda N