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Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

Bremelanotide (PT-141) has undergone more rigorous clinical investigation, though primarily in women

While B12 injections are typically safe, some people might experience slight swelling or irritation at the injection site

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The injection delivers B12 directly into the bloodstream, making it the most reliable method for patients with absorption problems, pernicious anaemia, or gastrointestinal conditions affecting B12 uptake (such as Crohn's disease, coeliac disease, or following gastric surgery)