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Symptoms That Should Never Be Ignored Certain severe symptoms demand immediate medical attention because they can signal a serious underlying issue

For example, alcohol causes the malfunctioning of biological signalling molecules by increasing the amount of ROS, while decreasing the levels of cellular antioxidants (267), leading to the accumulation of acetaldehyde (268) and causing cell apoptosis as a result of it inducing mitochondrial dysfunction (269)

Bulk and single-nucleus transcriptomics highlight intra-telencephalic and somatostatin neurons in Alzheimers disease