fh tirzepatide Beyond glycemia: Comparing to GLP-1 analogues | Reviews in Endocrine and Metabolic Disorders FullScopeMD | Tirzepatide (Injectable)

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Growth Hormone and Prolactin Excess. Lancet, 352 (9138), 14551461

Targeting these vulnerabilities aims to: Inhibit pathogenic effector cells Promote pro-resolution circuits Synergize with biologics & JAK inhibitors for control Strategic opportunity Portfolios spanning IL-17 inhibitors for psoriasis, IL-13 blockers for AD, JAK inhibitors for alopecia areata, and GLP-1 receptor agonists for obesity enable smart trials pairing targeted immunology with metabolic interventions tracking: Skin endpoints: PASI/EASI Systemic endpoints: HbA1c, adipokines Stratification: BMI/IR for personalized care Bottom line To move beyond symptom control, disrupt the metabolic fuel that sustains the inflammatory cascade

Bhatt DL, Szarek M, Pitt B, et al

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