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The transcription of a set of genes related to the regulation of heme synthesis and transformation, such as heme oxygenase 1 (HO-1), ferrochelatase (FECH) and SLC48A1, is upregulated by NRF2 [100,101,102,103]

Profile 4: Pediatric Patients Children requiring compounded medications for legitimate pediatric-dosing needs (a recognized use case for 503A compounding) should receive them from pharmacies with documented sterility testing and established pediatric compounding protocols

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Diabetologia 54 , 339349 (2011)