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Therefore, further large-scale studies are needed to further explore the therapeutic efficacy of GLP-1R agonists in patients with DPN

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Glucose-dependent insulinotropic polypeptide (GIP) GIP is a 42-amino acid peptide derived from preproGIP via post-translational processing by PC1/3, mainly within K cells in the duodenum and proximal jejunum (73)

While it is still in clinical development, trial data provides insights into how its typically studied