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For patients using PlexusDx compounded semaglutide or tirzepatide, sustained treatment and consistent dose adherence maximize the likelihood of durable weight loss and secondary blood pressure improvement

This setting may allow earlier insights into treatment effects, particularly via DNA-methylation based epigenetic clocks and other emerging aging biomarkers, which are recently being considered as outcome measures in double-blind, randomized geroscience trials 17 and global competitions testing gerotherapeutics 18

Among them, BSEP and MRP2 are the main two BA transporters

November 10, 2023

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