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Realistic timelines: Minimum 12-16 weeks to see significant visible changes Optimal 20-24 weeks for dramatic transformation 6+ months for major weight loss (50+ lbs) Remember: You're losing fat AND building muscle simultaneously

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If your hospital has a massive transfusion protocol and you think it may be needed due to large volume blood loss, activation of this protocol after the initial evaluation should be considered as well

The gradual dose escalation schedule (starting at 2.5 mg and increasing every 4 weeks) allows the GI system to adapt

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