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Addressing this, Dr Naseemuddin expresses, Weight regain is common after discontinuing GLP-1 therapy, but it is not inevitable

Excessive high-intensity training may therefore leave the body feeling more fatigued rather than energised

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In circadian regulation, STUB1 was identified as a selective BMAL1-binding protein in a mass spectrometry screening, with no observed interaction with CLOCK, indicating a specific role in targeting BMAL1 (Ullah et al., 2020)