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Unfortunately, a phase II clinical trial of UBX0101 (NCT03513016) was completed in patients with osteoarthritis and the promising results observed (Table 1), in vitro and in vivo, have not been up to the expectations in treated patients, leading only to a decrease of pain, without a significant improvement of the disease 30

2013) and extranodal extension diagnostics by deep learning algorithms was suggested (Kann et al

Moreover, autophagy is impaired in NASH, which is associated with defective autophagosome formation and reduced lysosomal acidification [76]

However, in many situations, this distinction is not possible because both lesions often have a deep location within the epineurium and similar imaging characteristics relative to the parent nerve [42]

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