Currently, it is indicated for patients with a BMI greater than 30% or a BMI greater than 27% with comorbidities
Doplnk stravy se nesm pouvat jako nhrada rozmanit stravy
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As an alternative, much more highly potent and specific Nrf2 activators have been studied, including the bardoxolone methyl analogue RTA 408, that has been shown to activate Nrf2 via KEAP1 inhibition [149]