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FDA-approved for its indicated uses

This benzimidazole lineage has progressed clinically, with VCT220 and HRS-7535 reporting positive Phase 3 results in China (HRS-7535 also in type 2 diabetes), despite earlier setbacks

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There is a boxed warning regarding thyroid C-cell tumors based on rodent studies, with a contraindication in patients with personal or family history of MTC or MEN2