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The Medicines and Healthcare products Regulatory Agency (MHRA) has warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using glucagon-like peptide-1 (GLP-1) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (GLP-1 RAs), who undergo surgery or procedures with general anaesthesia or deep sedation
As the body gets used to the medication, these side effects typically diminish or disappear
Angela Fitch, co-founder and chief medical officer of knownwell, a "weight-inclusive" healthcare company based in Boston, said she would caution against labeling any medication as an "everything drug," but agrees that GLP-1s show promise
The performance and financial cost of extended absence create motivation to explore off-label options despite regulatory and safety uncertainties
The study found that prescriptions for semaglutide were associated with lower overdose rates among patients with type 2 diabetes who also had a diagnosis of opioid use disorder (OUD)
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