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They next established that mitochondrial Coenzyme Q counteracted ferroptosis triggered by pharmacological and genetic inhibition of GPX4, suggesting that mitochondrial lipid redox signaling regulates ferroptosis in AML cells
Lin SH, Wang L, Myles B, Thall PF, Hofstetter WL, Swisher SG , Ajani JA, Cox JD, Komaki R, Liao Z
mechanism of action Inhibition of dopamine and norepinephrine reuptake: This is the therapeutic mechanism of action of bupropion
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