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Boehringer Ingelheim, in collaboration with Zealand Pharma, will likely be the next big challenger after advancing its promising candidate survodutide, a GCGR/GLP-1R dual agonist, to Phase 3 clinical trials last year

GLP-1s can help: Reduce appetite and slow digestion: GLP-1s mimic a hormone that signals fullness, helping you eat less without feeling deprived

rather, it exemplifies how endogenous peptide systems with pleiotropic signaling can be rendered clinically tractable through advances in peptide stabilization, pharmacokinetics, receptor bias, and dosing strategies

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