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Other options could be dermal treatments

Gastrointestinal side effects like nausea, vomiting, and constipation occur in both medications but tend to be more pronounced during semaglutide's titration phase due to its stronger receptor activation

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Schlezinger JJ, Struntz WD, Goldstone JV, Stegeman JJ: Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners