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however, it was discontinued in 2010 after a post-marketing study revealed statistical evidence of increased stroke and MIs in patients with preexisting CVD or diabetes

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The body is transitioning away from constant energy intake and frequent insulin spikes toward a more regulated and metabolically flexible state

33 Clinicians should educate individuals about the potential interactions between these substances and GLP-1s and routinely screen for substance use using validated short tools such as those proposed by the Institute of Medicine (now National Academy of Medicine) for Social and Behavioral Determinants of Health