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However, the role of neuroinflammation in LTP is not straightforward, moderate levels of inflammatory mediators might facilitate LTP, while excessive inflammation typically impairs synaptic plasticity

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Sources conflict on whether fosgonimeton is a prodrug of Dihexa or a structurally distinct molecule, so it should not be read as evidence for or against Dihexa specifically only as the nearest human data point in the program, and a negative one

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