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From Figures 1A,B, the most important residue positions for M pro recognition are, in descending order, P1, P2, P1, P4, and P3, with the first 3 being the major determinants, with the minimal P2-P1 consensus being LQ/(S,A,N,G)

Ward ZJ, Bleich SN, Cradock AL, et al

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This drug test cup is a reliable and accurate tool for detecting the presence of multiple drugs, including Ethyl Glucuronide, Fentanyl, K2 Synthetic Marijuana, and Tramadol