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In patients with severe gastrointestinal motility disorders, such as gastroparesis, this pharmacologic effect can intensify symptoms

Metabolism of 2-oxoaldehydes in yeasts

The trial, funded by Novo Nordisk, the manufacturer of Wegovy (semaglutide), found the drug improved liver inflammation, scarring (fibrosis), and sometimes both in people with metabolic dysfunction-associated steatohepatitis (MASH)

This lower dosing option was recently introduced to help reduce gastrointestinal side effects while maintaining efficacy and enabling smoother escalation than the original dosing strategy

It is one of the oldest independent biotech companies in the world