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Nausea Vomiting Diarrhea Stomach discomfort Reduced appetite In rare cases, more serious complications such as severe hypoglycemia may occur, particularly when used with other diabetes medications

Semaglutide exhibited potent BW-lowering effects in rodents

In the STEP-1 trial, once-weekly semaglutide 2.4 mg produced a mean weight loss of 14.9% vs 2.4% for placebo over 68 weeks in adults with overweight or obesity [5]

In some embodiments, the solution in step (a) includes 15-20% 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) and 0.1-0.3% trifluoroacetic acid by volume

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