In 2015, the FDA addressed the concerns with a Safety Communication stating that it is safe and that the studies showing that it wasnt safe were all flawed.[ref] Lets take a look at some of the studies and then dig into the mechanism of action
L., Sasakura, K., Nagano, T., Hanaoka, K
The research use version goes for roughly a fifth of that and is still enormously profitable, because bringing a real drug through trials to FDA approval is often estimated in the hundreds of millions of dollars, and by some counts well over a billion once you count the failures
This 48-week, randomized, double-blind, placebo-controlled study enrolled 338 adults with obesity or overweight with at least one weight-related comorbidity
PubMed Central, Vanuytsel, Tim, et al