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It activates the Akt survival pathway, recruits stem cells to injury sites, promotes endothelial cell differentiation for angiogenesis, and upregulates matrix metalloproteinases for tissue remodeling

They are not sustainable, which leads to regain, often more than what was lost

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We found a significant downregulation of CXCR4, CXCR1, CXCR2, CCR2 receptors on HUVEC cells exposed to cell products/CMs from all the PCa and BPH cell lines (Fig