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Your gut health directly impacts joint inflammation

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Doctors typically consider these medications only after other approaches such as nutrition changes, increased physical activity, and behavioral support have not been enough

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Another important substance, bile acid (BA) metabolites, are produced by microbial biotransformation of BA that pass through the enterohepatic circulation, which plays an important role in regulating intestinal inflammation by regulating immune cell maturation and cytokine release through farnesoid X receptor (FXR) and G protein-coupled receptor 5 (TGR5) receptors [117, 118]