cancer risk with semaglutide GLP-1s appear to cut risk. Researchers are asking why and how : NPR Weight-loss drugs may lower cancer

AOD-9604 stimulates lipolysis, which is the breakdown of fat, and inhibits lipogenesis, the process that transforms non-fat food materials into body fat

Injection-site reactions low single-digit incidence, mostly mild

The small size of substrates, which nutrient transporters can efficiently transport, limits the number of parent drug molecules for which the transporter-mediated prodrug delivery approach can be applied

A slight dip in the feeling of early satiety (feeling full quickly)

And of course the reporting tends to emphasise that its for those at risk of a heart attack or stroke, rather than those who have ALREADY had an event