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Both GLP-1 receptor agonists and glucose-dependent insulinotropic polypeptides are incretins

It plays a key role in glucose and appetite regulation by: Stimulating insulin release (glucose-dependent) Suppressing glucagon secretion Slowing gastric emptying Increasing satiety and reducing appetite In people with type 2 diabetes, this GLP-1 response is impaired leading to poor glycemic control

The amount of reduction of insulin dose should be determined on an individual basis based on prior diabetes control, risk of hypoglycemia and ketosis, type of GLP-1RA started, among others

The goal is to find a sustainable activity level that supports your overall health without exceeding your recovery capacity

Understanding these symptoms can help differentiate a semaglutide-induced rash from other skin conditions