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These neurons, however, express very low Gcg mRNA levels compared to Gcg in the lower brainstem, and it remains to be determined whether they may serve as a functionally relevant source of GLP-1 in local spinal cord circuits

Considering that several studies have associated the inhibition of central GLP-1R with aggravated glucose tolerance (36), we conducted oral glucose tolerance tests to investigate the role of LS GLP-1R neurons

In 1846 he demonstrated that when there is an excess of glucose in the blood it gets captured by the liver and stored there as a white starchy substance he called 'glycogen', which the liver turned back into glucose when glucose levels in blood got too low (Karamanou Protogerous Tsoucalas

Dahl, Y

At lower doses (4 mg and 8 mg), weight losses of 17.1 % and 22.8 % were recorded at 48 weeks