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In the absence of substrates, and with bound ADP, the catalytic cleft is in the open conformation, and the GLUD1 hexamers form long polymers in the crystal cell with more interactions than found in the abortive complex crystals (8AR8 [9] )
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In terms of targeted transport, Wang et al
Diese Verbindung ermglicht es den Fettsuren, die uere Membran der Mitochondrien zu passieren und in den inneren Raum, die sogenannte Matrix, zu gelangen