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"I'm always really leery about supplements because they aren't regulated in the same way medications are," she says

In the STEP 1 trial, once-weekly semaglutide 2.4 mg produced an average weight reduction of 14.9% compared with 2.4% with placebo over 68 weeks

Among enrolled participants, 10 declined participation , and 20 discontinued the intervention within the first month , primarily due to difficulties related to dietary adherence

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