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L-carnitine tartrate decreases SARS-CoV-2 infection of Calu-3 cells by downregulating ACE2 receptor expression Immune responses, clinical presentations and severity of outcomes vary notably among patients infected by COVID-19, and include muscle weakness, fever and respiratory complications

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10.1074/jbc.274.34.23740 J

Hypothesis-generating approaches Hypothesis-generating interventions rely on mechanistic reasoning or preliminary preclinical/clinical data, requiring further validation in humans

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