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Patients showed elevated insulin levels and a decrease in systolic blood pressure

Once lost, those gains were not fully restored by resuming treatment.

Table 3 also showed the results of the previous cycle and the subsequent cycle for 362 controls, without any adjuvant medication

The results showed that berberine prevented fructose-induced insulin resistance in rats by downregulating aldose reductase expression and inhibiting its enzymatic activity, therefore suppressing the polyol pathway that is overstimulated under hyperglycemia [66]