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And long-term use can have complications for some, like whats being called "Ozempic face." "So, what you tend to see is droopiness, or sagginess, or a really deflated look throughout the face from the temples, to the underlid, or tear trough area, through the cheek region, to the nasal and marionette lines, and the jaw, said Doctor Edward Davidson, a Cranial, Facial, & Cosmetic Plastic Surgeon with the Palm Beach Health Network