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Bella R, Biondi R, Raffaele R, Pennisi G

Example-3: Preparation- 1: Process for the preparation of Boc-His(Trt)-Aib-Glu(OtBu)-Gly-Thr(tBu)- Phe-Thr(tBu)-Ser(tBu)-Asp(OtBu)-Val-Ser(Oxa)-OH (fragment-7) Step-A: CTC resin (20 grams) was taken in a SPPS reactor and dichloromethane (120 mL) was added and allowed it to swell for 10 minutes

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Still, the hydrochloride form helps it suspend in water, preventing sedimentation and making it easy to consume

All new content was written by Michelle Liu, MPH, and medically reviewed by Kristen Fuller, MD