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Morphine reduces PVN Glu neuronal activity via MOR to induce constipation MOR activation has been shown to modulate neuronal function through well-established G protein signaling mechanisms, such as postsynaptic activation of G protein-coupled inwardly rectifying potassium channels, which causes hyperpolarization and inhibition of neurons 29,30,31

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[PubMed: 23235668] 232

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H.SongY

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Many people jump into peptide therapy without understanding how their lifestyle, timing, and pre-treatment choices affect the peptides effectiveness

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