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Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase

Moreover, SCFAs can enter the bloodstream and exert systemic effects, including the modulation of liver function and enhancement of liver detoxification pathways (104)

Tranexamic acid has skin whitening effects and is used topically as treatment for melasma

GraphPad Prism 6.0 software (La Jolla, CA, USA) was used for statistical analyses