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Eur J Pharm Sci 200:106838

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However, when a lung epithelial cell loses total CFTR expression, either by CF mutations, or experimentally by chemical or molecular means, the result has been reported to be loss of ACE2 expression and subsequent impairment of SARS-CoV-2 entry 39

Given that glial and neuronal cells undergo aging-related changes, including SASP, alterations in extracellular matrix composition, mitochondrial DNA release, and activation of inflammatory signaling pathways, shifts in membrane or lipid environments may influence these processes by modulating LLPS and domain dynamics

2020;105:e27106