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And unlike fat, muscle burns calories even at rest. Because of this, changes in muscle mass can influence energy needs and metabolic rate during weight loss

This suggests that joint levels largely reflect systemic levels, likely through passive distribution from the circulation

Two things change everything: Protein

That threshold drops to a BMI of 27, which is in the middle of the overweight category, for people who have a weight-related medical condition like type 2 diabetes, hypertension, or cholesterol

Personal Journal/Records: A detailed log of your symptoms, their severity, how they impacted your daily life, and any conversations with doctors regarding the side effects